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Hirofumi Mukai Selected Research

NK105

1/2019A multi-national, randomised, open-label, parallel, phase III non-inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients.
12/2016Phase I study of NK105, a nanomicellar paclitaxel formulation, administered on a weekly schedule in patients with solid tumors.

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Hirofumi Mukai Research Topics

Disease

94Breast Neoplasms (Breast Cancer)
03/2022 - 03/2002
45Neoplasms (Cancer)
01/2022 - 03/2002
19Neutropenia
09/2021 - 03/2007
8Stomatitis
04/2021 - 11/2014
7Neoplasm Metastasis (Metastasis)
09/2020 - 10/2012
6Diarrhea
09/2021 - 07/2008
5Exanthema (Rash)
10/2016 - 07/2008
5Disease Progression
09/2016 - 02/2009
4Fatigue
01/2022 - 04/2010
4Leukopenia
09/2021 - 06/2007
4Febrile Neutropenia
04/2021 - 02/2011
4Prostatic Neoplasms (Prostate Cancer)
12/2017 - 04/2014
4Carcinoma (Carcinomatosis)
07/2013 - 02/2003
3Mucositis
04/2021 - 10/2019
3Nausea
12/2017 - 08/2010
2Peripheral Nervous System Diseases (PNS Diseases)
02/2021 - 10/2020
2Lymphatic Metastasis
01/2021 - 08/2010
2Alopecia (Baldness)
11/2020 - 10/2016
2Thrombocytopenia (Thrombopenia)
01/2019 - 10/2015
2Vomiting
03/2017 - 08/2010
2Dyspnea (Shortness of Breath)
11/2014 - 10/2012
1Venous Thrombosis (Deep-Vein Thrombosis)
01/2022
1Cognitive Dysfunction
08/2021
1Vascular Remodeling
07/2021
1Thrombosis (Thrombus)
01/2021
1Anorexia
11/2020
1Amenorrhea
07/2020
1Neutropenic Enterocolitis
01/2020
1Intestinal Perforation
01/2020
1Ovarian Neoplasms (Ovarian Cancer)
01/2020
1Sarcoma (Soft Tissue Sarcoma)
09/2019
1Uterine Cervical Neoplasms (Cancer of the Cervix)
09/2019
1Microsatellite Instability
09/2019

Drug/Important Bio-Agent (IBA)

22Trastuzumab (Herceptin)FDA Link
03/2022 - 03/2002
17Hormones (Hormone)IBA
09/2021 - 06/2010
15Estrogen ReceptorsIBA
10/2021 - 08/2010
15ErbB Receptors (EGF Receptor)IBA
09/2021 - 12/2012
14taxaneIBA
01/2022 - 08/2010
9human ERBB2 proteinIBA
03/2022 - 10/2009
8exemestane (Aromasin)FDA Link
04/2021 - 05/2013
8EverolimusFDA Link
04/2021 - 05/2013
8palbociclibIBA
03/2021 - 06/2016
7eribulinFDA Link
07/2021 - 10/2012
7Paclitaxel (Taxol)FDA LinkGeneric
01/2019 - 08/2010
7Docetaxel (Taxotere)FDA Link
03/2017 - 02/2003
5Biomarkers (Surrogate Marker)IBA
10/2021 - 04/2010
5AnthracyclinesIBA
10/2021 - 01/2013
5Letrozole (Femara)FDA LinkGeneric
01/2020 - 11/2014
5Pharmaceutical PreparationsIBA
12/2017 - 07/2008
5Taxoids (Taxanes)IBA
01/2016 - 08/2010
5Aromatase InhibitorsIBA
01/2015 - 06/2010
4Epidermal Growth Factor (EGF)IBA
10/2021 - 01/2013
4Dexamethasone (Maxidex)FDA LinkGeneric
04/2021 - 02/2003
4Lapatinib (GW572016)FDA Link
05/2015 - 01/2007
4Anastrozole (Arimidex)FDA LinkGeneric
11/2014 - 06/2010
3130-nm albumin-bound paclitaxelIBA
01/2022 - 02/2021
3Progesterone Receptors (Progesterone Receptor)IBA
10/2021 - 01/2016
3Doxorubicin (Adriamycin)FDA LinkGeneric
07/2020 - 03/2007
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
07/2020 - 06/2007
3Biological ProductsIBA
06/2018 - 01/2013
3TamoxifenFDA LinkGeneric
11/2014 - 06/2010
3Cisplatin (Platino)FDA LinkGeneric
12/2013 - 02/2003
3Phosphotransferases (Kinase)IBA
02/2009 - 01/2007
2Fulvestrant (Faslodex)FDA Link
09/2021 - 03/2019
2Anti-Bacterial Agents (Antibiotics)IBA
04/2021 - 07/2016
2Antineoplastic Agents (Antineoplastics)IBA
01/2020 - 08/2010
2Carboplatin (JM8)FDA LinkGeneric
01/2020 - 01/2019
2GemcitabineFDA Link
01/2020 - 12/2013
2Cyclin-Dependent Kinase 4IBA
01/2019 - 06/2016
2NK105IBA
01/2019 - 12/2016
2Androgen Receptor AntagonistsIBA
12/2017 - 12/2017
2darolutamideIBA
12/2017 - 12/2017
2Fluorouracil (Carac)FDA LinkGeneric
01/2016 - 08/2010
2cabazitaxelFDA Link
10/2015 - 04/2014
2EnzymesIBA
11/2014 - 07/2008
2titanium silicide (TS-1)IBA
07/2014 - 08/2010
2Tyrosine (L-Tyrosine)FDA Link
02/2009 - 01/2007
1vinyltriethoxysilane (VTES)IBA
01/2022
1Formaldehyde (Formol)FDA Link
10/2021
1ParaffinIBA
10/2021
1TubulinIBA
10/2021
1pyrimidineIBA
10/2021
1abemaciclibIBA
09/2021
1Benzethonium (Magic, Formula)IBA
04/2021
1pegfilgrastim (Neulasta)FDA Link
04/2021
1Ointments (Pastes)IBA
04/2021
1Albumin-Bound PaclitaxelFDA Link
02/2021
1Bevacizumab (Avastin)FDA Link
01/2020
1NivolumabIBA
09/2019

Therapy/Procedure

39Therapeutics
03/2022 - 03/2002
35Drug Therapy (Chemotherapy)
03/2022 - 06/2003
8Neoadjuvant Therapy
03/2021 - 03/2007
6Radiotherapy
04/2021 - 01/2013
6Drug Tapering
01/2020 - 10/2015
4Adjuvant Chemotherapy
03/2022 - 12/2013
4Castration
12/2017 - 04/2014
3Combination Drug Therapy (Combination Chemotherapy)
01/2020 - 02/2003
3Complementary Therapies (Alternative Medicine)
01/2018 - 12/2006
2Duration of Therapy
01/2019 - 06/2018
1Dentures
04/2021